15-07-2023, 09:44 PM
Quote:Sickle-cell anemia does not prove evolution!Sickle-cell anaemia is caused by an inherited defect in the instructions which code for the production of haemoglobin, the oxygen-carrying pigment in red blood cells. You will only develop the full-blown, serious disease if both of your parents have the defective gene. If you inherit the defect from only one parent, the healthy gene from the other one will largely enable you to escape the effects of this serious condition.
However, this means you are capable of transmitting the defective gene to your offspring, and it also happens that such carriers are less likely to develop malaria, which is often fatal. Being a carrier of sickle-cell disease without suffering it (heterozygosity is the technical term) is far more common in those areas of the world which are high-risk malaria areas, especially Africa.
This is good evidence that natural selection plays a part in maintaining a higher frequency of this carrier state. If you are resistant to malaria, you are more likely to survive to pass on your genes. Nevertheless, it is a defect, not an increase in complexity or an improvement in function which is being selected for, and having more carriers in the population means that there will be more people suffering from this terrible disease. Demonstrating natural selection does not demonstrate that ‘upward evolution’ is a fact, yet many schoolchildren are taught this as a ‘proof’ of evolution.

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