28-02-2024, 07:53 PM
we have to study mechanics as part of my college academics. and we had a mechanics assignment, and one day last week, me and my friends were joking about how a biomedical engineering female friend in the circle is gonna study muh torsional stress on people's back and analyze it. basically some meta jokes related to our daily lives.
and later that night, i was in my room doing some research related to my internship (cancer diagnosis and genetics) and i was texting the same friends. I then jokingly searched for DNA friction as i thought it was pretty funny.
to my surprise... friction between DNA and RNA molecules... was a real thing
and to make it even funnier and brutal.
it affected gene expression by affecting transcription and translation processes (basically the mechanisms through which ur body produces proteins based on ur genes)
so to summarize, basically, the reason ur genes ARE not expressed to the full extent... is because of fucking friction in ur body
u cant make this shit up
https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.118.268101
https://academic.oup.com/nar/article/46/12/5924/5026267
https://link.springer.com/article/10.1007/s12551-016-0216-8
https://www.annualreviews.org/doi/10.1146/annurev.biochem.70.1.369
(check references in the articles for the papers, there's a lot of papers on this, im not a subject matter expert, only went though like 30 of them)
this makes instant sense when u think about it, they are physical molecules at the end of the day, and so mechanics DOES apply to them too.
but who wouldve thought it was so important
and later that night, i was in my room doing some research related to my internship (cancer diagnosis and genetics) and i was texting the same friends. I then jokingly searched for DNA friction as i thought it was pretty funny.
to my surprise... friction between DNA and RNA molecules... was a real thing
and to make it even funnier and brutal.
it affected gene expression by affecting transcription and translation processes (basically the mechanisms through which ur body produces proteins based on ur genes)
so to summarize, basically, the reason ur genes ARE not expressed to the full extent... is because of fucking friction in ur body
u cant make this shit up
https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.118.268101
https://academic.oup.com/nar/article/46/12/5924/5026267
https://link.springer.com/article/10.1007/s12551-016-0216-8
https://www.annualreviews.org/doi/10.1146/annurev.biochem.70.1.369
(check references in the articles for the papers, there's a lot of papers on this, im not a subject matter expert, only went though like 30 of them)
this makes instant sense when u think about it, they are physical molecules at the end of the day, and so mechanics DOES apply to them too.
but who wouldve thought it was so important
